Cultured myoblasts repair recipient myoblasts and myofibers genetically and phenotypically by fusion
Myoblasts are somatic muscle progenitor cells
Every myoblast is a medicinal chest containing a human genome, organelles and epigenetic factors
Myoblasts divide extensively without being tumorigenic
Myoblasts fuse into multinucleated myotubes, lose major histocompatibility Class-I (MHC-1) antigens within 1 week after fusion, and develop into young muscle fibers
Myoblasts fuse to form multinucleated myotubes, sharing their nuclei
Myotubes repenish and regenerate myofibers to augment contractile activity
CNN on "Saving Your Life"
Heart disease remains the most common cause of death worldwide. CNN Chief Medical Correspondent Dr. Sanjay Gupta shared a story about experimental myoblast transplant on heart patient.
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